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Anti-Opsin antibody, Mouse monoclonal
| 产品编号： | 4111700 |
| 规格： | clone RET-P1, purified from hybridoma cell culture |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Opsin antibody, Mouse monoclonal
Anti-Opsin 2
Anti-Rhodopsin
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-Opsin antibody, Mouse monoclonal (rhodopsin) (mouse IgG1 isotype) is derived from the RET-P1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/C mice immunized with rat retinal membranes. Opsin is also called as rhodopsin protein, members of the G-protein coupled receptor (GPCR) superfamily. Opsin comprises >95% of the rod outer segments (ROS) intrinsic membrane and consists of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal. |
| Application【应用】 | Anti-Opsin antibody has been used in
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| Biochem/physiol Actions【生化/生理作用】 | Opsin is an essential molecules for mediating the ability of animals to detect and use light for diverse biological functions. Mutations in the opsin (rhodopsin) gene are linked to retinitis pigmentosa (RP), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness. |
| Other Notes【其他说明】 | rat retinal membranes |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| clone【克隆】 | RET-P1, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~39 kDa |
| species reactivity | rabbit, turtle, fish, amphibian, human, avian, rat, mouse, bovine |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: suitable immunoblotting: 2-4 μg/mL using human retinoblastoma Y79 cell line extract. immunofluorescence: suitable immunohistochemistry: 5-10 μg/mL using rat eye frozen sections. radioimmunoassay: suitable |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P08100 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | rat ... Rho(24717) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
