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Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Cy5 conjugate
产品别名
Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Cy5 conjugate
H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. |
| Specificity【特异性】 | Histone H3 phosphorylated at Ser10 Expected to cross react with all vertebrate species. |
| Immunogen【免疫原】 | A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3, clone 3H10. This is a Cy5 conjugate of Anti-phospho-Histone H3 (Ser10), clone 3H10, Catalog # 05-806. |
| Application【应用】 | Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Cy5 Conjugate is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p, is labeled with Cy5.5 NHS ester (Cy5) and validated in IF, WB. Research Sub Category Histones Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Routinely evaluated by immunoblot in acid extrated protein from mitotic HeLa cells treated with colcemid (17-306). |
| Physical form【外形】 | Protein G Purified |
| Analysis Note【分析说明】 | Control Acid extracts from colcemid treated HeLa cells (lane 2) |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | CY5 conjugate |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 3H11, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Upstate® |
| technique(s) | immunofluorescence: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NM_003493.2 |
| UniProt accession no.【UniProt登记号】 | Q16695 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... HIST1H3F(8968) |
产品说明
| Target description【目标描述】 | 17kDa |
| Storage and Stability【储存及稳定性】 | 1 year at 4°C from date of shipment |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
