Nifedipine-CAS 21829-25-4-Calbiochem

C₁₇H₁₈N₂O₆

346.33

MFCD00057326

Relatively selective blocker of L-type Ca²⁺ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca²⁺ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.
Relatively selective blocker of L-type Ca²⁺ channels. One of the most extensively studied Ca²⁺ channel blockers of 1,4-dihydropyridine-type and a pharmacologically useful vasodilator. Induces apoptosis in human glioblastoma cells.

Product does not compete with ATP.
Reversible: no
Primary Target
L-type Ca2+ channels
Cell permeable: no

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (UV)

solid

Calbiochem^®

OK to freeze
protect from light

yellow

DMSO: soluble
ethanol: soluble

ambient

10-30℃

1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3

HYIMSNHJOBLJNT-UHFFFAOYSA-N

250 mg in Plastic ampoule

GHS07

Warning

H302

P264 - P270 - P301 + P312 - P501

Acute Tox. 4 Oral

11 - Combustible Solids

WGK 1