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HIF Inhibitor VI-Calbiochem
| 产品编号： | 4084063 |
| 规格： | The HIF-1 Inhibitor, NSC-134754 controls the biological activity of HIF-1. This small molecule/inhibitor is primarily used for Cell Structure applications. |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
HIF Inhibitor VI-Calbiochem
NSC-134754
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H34N2O2 |
| Molecular weight | 418.57 |
| General description【一般描述】 | A cell-permeable emetan derivative that selectively reduces HIF-1 activity by 73% in a luciferase reporter assay, and blocks HIF-1α protein induction in response to DFX, hypoxia, and IGF-1 in U2OS-HRE-luc cells at 10 µM, without significantly inhibiting cell growth. Furthermore, it is shown to completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells. |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Chau, N.M., et al. 2005. Cancer Res.65, 4918. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | brown |
| solubility【溶解性】 | DMSO: 50 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
