D-(–)-2-Amino-5-phosphonopentanoic Acid-CAS 79055-68-8-Calbiochem

C₅H₁₂NO₅P

197.13

MFCD00078839

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.
Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
NMDA receptor antagonist

Toxicity: Irritant (B)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
Schulte, M.K., et al. 1994. Brain Res. 649, 203.
Davis, S., et al. 1992. J. Neurosci. 12, 21.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥97% (HPLC)

solid

Calbiochem^®

OK to freeze
desiccated (hygroscopic)
protect from light

white

dilute aqueous base: 1 mg/mL
water: 1 mg/mL

ambient

2-8℃

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1

VOROEQBFPPIACJ-SCSAIBSYSA-L

5 mg in Plastic ampoule

11 - Combustible Solids

WGK 3