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Anti-FBXO31 antibody produced in rabbit

产品编号:3362026
规格:affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3362026100 μL6300
产品别名

Anti-FBXO31 antibody produced in rabbit

Anti-DKFZP434B027

Anti-DKFZp434J1815

Anti-FBX14

Anti-FBXO14

Anti-FLJ22477

基本信息
NACRES
NA.41
Immunogen【免疫原】
Synthetic peptide directed towards the middle region of human FBXO31
Biochem/physiol Actions【生化/生理作用】
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Sequence【序列】
Synthetic peptide located within the following region: VAAAEQPAQCGQGQPFVLPVGVSSRNEDYPRTCRMCFYGTGLIAGHGFTS
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
40 kDa
species reactivity
dog, human, mouse, bovine
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NM_024735
UniProt accession no.【UniProt登记号】
Q5XUX0
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... FBXO31(79791)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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