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Anti-CD137 antibody produced in goat
产品编号: | 3351985 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 0.1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-CD137 antibody produced in goat
Anti-4-1BB
基本信息
MDL number | MFCD01094424 |
NACRES | NA.41 |
General description【一般描述】 | CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor superfamily. It is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. |
Immunogen【免疫原】 | mouse myeloma cell line NS0-derived recombinant human 41BB/TNFRSF9/CD137 Leu24Gln186 |
Application【应用】 | Anti-CD137 antibody produced in goat is suitable for the following applications:
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Biochem/physiol Actions【生化/生理作用】 | CD137 in T lymphocytes helps to regulate activation, proliferation and apoptosis. CD137 and CD28 are co-stimulatory molecules of T cell activation. It plays an important role in regulating T-cell-dependent immune responses. The expression of CD137 correlates negatively with lymphocyte proliferation and induces cell death caused by mitogen overstimulation. In monocytes, CD137 induces activation, promotes adherence and helps in prolongs survival. |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
Reconstitution【重悬】 | Reconstitute at 0.2 mg/mL in sterile PBS |
产品性质
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | capture ELISA: 0.2-0.8 μg/mL flow cytometry: 2.5 μg using 106 human T cells treated with PHA immunocytochemistry: 5-15 μg/mL western blot: 0.1 μg/mL |
impurities【杂质】 | <0.10 EU/μg endotoxin |
UniProt accession no.【UniProt登记号】 | Q07011 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TNFRSF9(3604) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |