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PF-04753299
产品别名
1289620-49-0
PF-04753299
PF 04753299
(+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide
PF-4753299
α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide
(2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H21NO4S |
| Molecular weight | 347.43 |
| MDL number | MFCD22683864 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823811 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to light brown |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | room temp |
| SMILES string | O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2 |
| InChI | 1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1 |
| InChI key | GDYIQUFNICPYHF-GOSISDBHSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
