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Penciclovir
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3179748 | 100 MG | 2180 | 2-5天 | 4-6周 |
产品别名
39809-25-1
Penciclovir
BRL-39123
2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H15N5O3 |
| Molecular weight | 253.26 |
| MDL number | MFCD15142866 |
| PubChem Substance ID【PubChem化学物质编号】 | 329819986 |
| Application【应用】 | Penciclovir is a selective antiherpesvirus agent, particularly against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and varicella-zoster virus (VZV). |
| Biochem/physiol Actions【生化/生理作用】 | Penciclovir is converted to its active form, penciclovir triphosphate, by cellular kinases. It inhibits viral DNA polymerase by competing with deoxyguanosine triphosphate. It inhibits DNA synthesis of virus-infected cells. Penciclovir has in vitro activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2). It does not inhibit DNA synthesis in non-infected cells. Mode of resistance is via qualitative changes in viral thymidine kinase or DNA polymerase. |
| Other Notes【其他说明】 | Keep container tightly closed in a dry and well-ventilated place. |
产品性质
| Quality Level【质量水平】 | 100 |
| solubility【溶解性】 | 0.02 M potassium phosphate: soluble 2 mg/mL |
| Mode of action【作用机制】 | DNA synthesis | interferes enzyme | inhibits |
| antibiotic activity spectrum【抗生素抗菌谱】 | viruses |
| SMILES string | NC1=NC(=O)c2ncn(CCC(CO)CO)c2N1 |
| InChI | 1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18) |
| InChI key | JNTOCHDNEULJHD-UHFFFAOYSA-N |
| packaging【包装】 | 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
