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Neurogenesis Inducer V, KHS101-Calbiochem
| 产品编号： | 4168001 |
| 规格： | A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Neurogenesis Inducer V, KHS101-Calbiochem
N4-Isobutyl-N2-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H21N5S |
| Molecular weight | 339.46 |
| MDL number | MFCD18206916 |
| General description【一般描述】 | A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2). Shown to significantly induce neuronal differentiation of cultured rat hippocampal NPCs (neural progenitor cells; EC50 ~ 1 µM) and in adult rats (6 mg/kg, s.c.) and suppress proliferation. |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Wurdak, H., et al. 2010. Proc. Natl. Acad. Sci. USA107, 16542 |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | resin (Sticky) |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: 100 mg/mL |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 10 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
