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CTF1, GST tagged human
| 产品编号： | 4117616 |
| 规格： | recombinant, expressed in E. coli, ≥70% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
CTF1, GST tagged human
NF-I
CTF
NF-1
CTF/NFI
基本信息
| NACRES | NA.26 |
| Biochem/physiol Actions【生化/生理作用】 | The CCAAT-box binding protein 1 (CTF1, also called NF-I or NF-1) is a proline-rich transcription activator. It selectively activates transcription of genes that contain GCCAAT consensus sequence in the promoter region, including human Ha-Ras, alpha-globin, hsp70 and many other cellular and viral genes. Cloning and functional characterization of the protein revealed that CTF1 contains a N-terminal DNA binding domain and a C-terminal proline-rich activation domain. CTF1 was shown to interact with the general transcription factor IIB (TFIIB) and facilitate the recruitment of TFIIB to TBP-DNA complexes, with the forkhead thyroid transcription factor TTF2 to regulate hormone-dependent transcription of thyroperoxidase gene, as well as other receptor proteins to synergize hormone receptor-responsive activation. |
| Physical form【外形】 | Clear and colorless frozen liquid solution |
| Preparation Note【制备说明】 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~36.8 kDa |
| packaging【包装】 | pkg of 10 μg |
| concentration【浓度】 | 650 μg/mL |
| color【颜色】 | colorless to clear |
| NCBI accession no.【NCBI登记号】 | X12492 |
| UniProt accession no.【UniProt登记号】 | Q16619 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human herpesvirus 2 ... CTF-1(1489) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
