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CD24 (mouse): FC (human)
| 产品编号： | 4117184 |
| 规格： | recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
CD24 (mouse): FC (human)
X62 Heat stable antigen (HSA)
NaMN adenylyltransferase 1
M1/69-J11D heat stable antigen
Nectadrin
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns). |
| Physical form【外形】 | Lyophilized from PBS. |
| Reconstitution【重悬】 | Reconstitute with 50 μL deionized water. |
| Other Notes【其他说明】 | Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1. |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in HEK 293 cells |
| Assay【测定】 | >90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~50 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 50 μg |
| impurities【杂质】 | <0.06 EU/μg endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P24807 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... CD24(100133941) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
