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VU0359595
| 产品编号： | 4095789 |
| 规格： | (1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide, powder |
| CAS NO： | 1246303-14-9 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246303-14-9
VU0359595
EVJ; VU0359595
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H29BrN4O2 |
| Molecular weight | 497.43 |
| NACRES | NA.25 |
| General description【一般描述】 | VU0359595 has been shown to selectively inhibit the PLD1 isoform at nM levels (see data below). **Images added as .gif in folder |
| Application【应用】 | VU0359595 has been used as PLD2 (phospholipase D2) inhibitor to quantitatively address functional and molecular aspects of the involvement of PLD-derived phosphatidic acid (PA) in regulated exocytosis and as PLD1 inhibitor to treat the knockout mice to study its effects on them. |
| Biochem/physiol Actions【生化/生理作用】 | VU0359595 helps to block phospholipase D (PLD) which in turn reduces deoxyribonucleoside triphosphate (dNTP) biosynthesis in glioma models. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 857371P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (857371P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
