DChemsPC

C₇₀H₁₁₆NO₁₂P

1194.64

NA.25

DChemsPC might be used:

• as a substitute for cholesterol in liposome formulation to study its effect on membrane stability
• in the preparation of pH-gradient liposomes
• to form sterol-phospholipid hybrid with palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine (PCholPC) and to study its properties and interactions

Liposome instability in blood is caused mainly due to cholesterol exchange. Sterol modified phospholipid retains the bilayer-stabilizing effect of free cholesterol, inhibiting its transfer from the bilayer. Therefore, disterolphospholipids are ideal for liposome preparation. The use of DChemsPC in liposomes prevents content leaking into the serum.

powder

Avanti Polar Lipids 880346P

dry ice

−20℃

O=P([O-])(OCC[N+](C)(C)C)OC[C@H](OC(CCC(OC1CC[C@]2(C)C(C1)=CCC3C2CC[C@]4(C)C3CC[C@H]4[C@@H](C)CCCC(C)C)=O)=O)COC(CCC(OC5CC[C@]6(C)C(C5)=CCC7C6CC[C@]8(C)C7CC[C@H]8[C@@H](C)CCCC(C)C)=O)=O

5 mL Amber Glass Screw Cap Vial (880346P-25mg)

13 - Non Combustible Solids

WGK 3