AMPK (α1/β1/γ1), active, His tagged human

NA.32

AMPK is a heterotrimer protein kinase consisting of a α catalytic subunit, and non-catalytic β and γ subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol.

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

200

expressed in baculovirus infected Sf9 cells

PRECISIO^® Kinase

≥70% (SDS-PAGE)

buffered aqueous glycerol solution

626-848 nmol/min·mg

A1 subunit ~68 kDa
B1 subunit ~38 kDa
G1 subunit ~40 kDa

P54619
Q13131
Q9Y478

dry ice

−70℃

human ... PRKAA1(5562), PRKAB1(5564), PRKAG1(5571)

GHS07,GHS08

Danger

H315 - H319 - H360D

P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 1

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter