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α2-巨球蛋白 来源于人类血浆
α2-Macroglobulin from human plasma
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4087306 | 5 MG | 21540 | 2-5天 | 4-6周 |
产品别名
1631137-21-7
α2-巨球蛋白 来源于人类血浆
α2-Macroglobulin from human plasma
α2-M
基本信息
| MDL number | MFCD00130472 |
| NACRES | NA.61 |
| Application【应用】 | 通过与蛋白酶形成 1:1 复合物抑制各种内切蛋白酶。当蛋白酶裂解巨球蛋白"诱饵"序列时，巨球蛋白将重排并捕获蛋白酶。 |
| Biochem/physiol Actions【生化/生理作用】 | α2-Macroglobulin is found abundantly in plasma and interstitial fluids. The protease-α2-M balance plays an important role in mediating inflammatory tissue destruction. Serum levels of α2-M and protease-α2-M complexes are increased in patients with sepsis, emphysema, periodontitis, rheumatoid arthritis, and other inflammatory diseases, and oxidant inactivation of α2-M may contribute to tissue destruction during inflammation. |
| Analysis Note【分析说明】 | 100 mg solids are lyophilized with 1 mg glycine from 35.2 mL 30 mM sodium phosphate, pH 7.0 经检测，每位捐献者的血浆 HIV-1/HIV-2 抗体、HCV 和 HbSAg 抗体均为阴性。 |
| Other Notes【其他说明】 | Conformational changes of α2-M |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | human plasma |
| Assay【测定】 | ≥90% (GE) |
| mol wt【分子量】 | ~720 kDa (four glycoprotein subunits) |
| technique(s) | cell culture | mammalian: suitable |
| solubility【溶解性】 | H2O: 1 mg/mL, clear to faintly turbid, colorless to faintly yellow |
| UniProt accession no.【UniProt登记号】 | P01023 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... A2M(2) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
