c-Myc Inhibitor-CAS 403811-55-2-Calbiochem

C₁₂H₁₁NOS₂

249.35

MFCD00758517

A cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (Effective concentration: 64 µM using c-Myc-transfected Rat1a fibroblasts).
A cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
c-Myc

Toxicity: Carcinogenic / Teratogenic (D)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Yin, X., et al. 2003. Oncogene22, 6151.

Sold under license of U.S. Patent 7,026,343.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (sum of two isomers, HPLC)

solid

Calbiochem^®

OK to freeze
protect from light

yellow

DMSO: 200 mg/mL

ambient

2-8℃

10 mg in Plastic ampoule
Packaged under inert gas

GHS07

Warning

H317 - H319

P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

Eye Irrit. 2 - Skin Sens. 1

11 - Combustible Solids

WGK 3