您的位置：首页 > 产品中心 > 664969-54-4， LF3
LF3
产品别名
664969-54-4
LF3
N-[4-(Aminosulfonyl)phenyl]-4-(3-phenyl-2-propen-1-yl)-1-piperazinecarbothioamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H24N4O2S2 |
| Molecular weight | 416.56 |
| Biochem/physiol Actions【生化/生理作用】 | LF3 is a potent inhibitor of Wnt/β-catenin signaling that suppresses cancer cells motility, cell-cycle progression, and the overexpression of Wnt target genes. LF3 is a potent and specific antagonist of the interaction between β-catenin and the transcription factor TCF4. LF3 blocks self-renewal of cancer stem cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | S=C(NC1=CC=C(S(N)(=O)=O)C=C1)N2CCN(C/C=C/C3=CC=CC=C3)CC2 |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
