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GRL-0617
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086742 | 5 MG | 1091 | 2-5天 | 4-6周 | |
| 4086742 | 25 MG | 3820 | 2-5天 | 4-6周 |
产品别名
1093070-16-6
GRL-0617
GRL0617
5-Amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide
GRL 0617
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H20N2O |
| Molecular weight | 304.39 |
| MDL number | MFCD12547683 |
| Biochem/physiol Actions【生化/生理作用】 | GRL-0617 is a cell penetrant non-cytotoxic and potent inhibitor of the SARS-CoV -2 papain-like protease (SCoV2-PLpro) and SCoV-PLpro. GRL-0617 reversibly binds to SCoV2-PLpro and disrupts its interaction with Interferon-stimulated gene 15 (ISG15). GRL-0617 poorly affects (> 100 μM) the activities of MERS PLpro, a series of cysteine proteases, including the human deubiquitinating enzymes HAUSP, USP18, UCH-L1, UCH-L3, and a papain-like protease (PLP2) from the human coronavirus NL63. GRL-0617 suppress SARS-CoV-2 infection and promote anti-viral immunity. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -72.0 to -82.0°, c = 0.5 in chloroform-d |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
