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BIQ
产品别名
223387-75-5
BIQ
FG-2216
IOX 3
YM 311
[[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid
FG 2216
N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H9ClN2O4 |
| Molecular weight | 280.66 |
| MDL number | MFCD23136998 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826079 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | BIQ (FG-2216) is an orally available and potent inhibitor of prolyl-hydroxylase (PHD). BIQ induces significant and reversible plasma erythropoietin (EPO) levels in vitro and in hemodialysis patients. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC1=C(C(NCC(O)=O)=O)N=C(Cl)C2=CC=CC=C21 |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
