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Tizoxanide
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086439 | 5 MG | 958 | 2-5天 | 4-6周 | |
| 4086439 | 25 MG | 3360 | 2-5天 | 4-6周 |
产品别名
173903-47-4
Tizoxanide
2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide
Nitazoxanide metabolite
Desacetyl-NTZ
NTZ metabolite
Desacetyl-nitazoxanide
TIZ
2-Hydroxy-N-(5-nitrothiazol-2-yl)benzamide
NSC 697856
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H7N3O4S |
| Molecular weight | 265.25 |
| MDL number | MFCD07484970 |
| Biochem/physiol Actions【生化/生理作用】 | Tizoxanide (TIZ) is the active metabolite of the broad-spectrum parasiticidal drug nitazoxanide (NTZ), a noncompetitive inhibitor against bacterial pyruvate-ferredoxin oxidoreductase (PFOR Ki 2 to 10 μM). NTZ deacetylates rapidly to TIZ in plasma (t1/2 ~6 min at 37℃ in human plasma) and in the presence of liver microsomes. NTZ is also reported to exhibit antiviral activity against Hepatitis C, Norovirus, Paramyxovirus, Influenza, Vaccinia, and Zika. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=C(C(NC2=NC=C([N+]([O-])=O)S2)=O)C=CC=C1 |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
