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SK-216
产品别名
654080-03-2
SK-216
SK 216
2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]-propanedioic acid sodium salt
[5-[[6-[5-(1,1-dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]-propanedioic acid disodium salt
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C29H29NNa2O6 |
| Molecular weight | 533.52 |
| Biochem/physiol Actions【生化/生理作用】 | SK-216 is an orally active potent and selective inhibitor of Plasminogen activator inhibitor-1 (PAI-1) that inhibits tumor progression and angiogenesis. SK-216 inhibits migration and tube formation of cultured human umbilical vein endothelial cells induced by various angiogenic factors. SK-116 prevents a formation of gastro-intestinal polyps in Min mice. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 0.5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | room temp |
| SMILES string | CC(C)(C)C(C=C1)=CC2=C1OC(C3=CC=C4C(C=CC(OCCCCCC(C([O-])=O)C([O-])=O)=C4)=C3)=N2.[2Na+] |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
