您的位置：首页 > 产品中心 > 1253-84-5， 5α,6β-dihydroxycholestanol
5α,6β-dihydroxycholestanol
产品别名
1253-84-5
5α,6β-dihydroxycholestanol
3β,5α,6β-Trihydroxycholestane
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H48O3 |
| Molecular weight | 420.67 |
| NACRES | NA.25 |
| General description【一般描述】 | 5α,6β-dihydroxycholestanol is a structural derivative of cholesterol. It is produced by the low-density lipoprotein oxidation (LDL) and is a cholesterol autooxidation product. 5α,6β-dihydroxycholestanol is an abundant oxysterol. |
| Application【应用】 | 5α,6β-dihydroxycholestanol has been used as a cholesterol oxidation product in reversed phase chromatography (RP-HPLC) and mass spectroscopy analysis. It may be used as an internal standard in tandem mass spectrometry (MS/MS analysis) of plasma samples. |
| Biochem/physiol Actions【生化/生理作用】 | 5α,6β-dihydroxycholestanol (5α,6α-diOH-Chol) or cholestan-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It exhibits neuroprotective functionality during central nervous system (CNS) ischemia. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700054P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C27H48O3/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24(29)27(30)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28-30H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27+/m1/s1 |
| InChI key | YMMFNKXZULYSOQ-RUXQDQFYSA-N |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700054P-25mg) 5 mL Amber Glass Screw Cap Vial (700054P-5mg) |
安全信息
| Hazard Statements | H413 |
| Precautionary Statements | P273 - P501 |
| Hazard Classifications【危险分类】 | Aquatic Chronic 4 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
