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O-Desmethyl gefitinib
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4085872 | 5 MG | 6730 | 2-5天 | 4-6周 |
产品别名
847949-49-9
O-Desmethyl gefitinib
4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol
O-Desmethylgefitinib
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H22ClFN4O3 |
| Molecular weight | 432.88 |
| General description【一般描述】 | O-Desmethyl gefitinib is a major active metabolite of gefitinib. It is a potent EGFR (erbB1/HER1) inhibitor (IC50 = 36 nM). Gefitinib is metabolized by CYP2D6 to O-Desmethyl gefitinib. Gefitinib is an EGFR inhibitor that is used to treat some types of cancers. |
| Application【应用】 | Metabolomics research |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | synthetic |
| grade【等级】 | research grade |
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| technique(s) | HPLC: suitable |
| color【颜色】 | light yellow to yellow |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
