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20:0(2S-OH) Ceramide
| 产品编号： | 4084557 |
| 规格： | N-(2′-(S)-hydroxyarachidoyl)-D-erythro-sphingosine, powder |
| CAS NO： | 1246298-48-5 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246298-48-5
20:0(2S-OH) Ceramide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C38H75NO4 |
| Molecular weight | 610.01 |
| NACRES | NA.25 |
| General description【一般描述】 | Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration. |
| Biochem/physiol Actions【生化/生理作用】 | Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an antitumor drug to exhibit its activity. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860820P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCCCCC)=O)CO |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860820P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
