Protein Kinase Cν (PKCν) Active human

MFCD07371119

NA.32

Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 ℃ using a final concentration of 50 μM [³²P] ATP.

PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.

Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol

200

expressed in E. coli

≥75% (SDS-PAGE)

buffered aqueous glycerol solution

protein apparent mol wt ~142 kDa

O94806

dry ice

−70℃

human ... PRKD3(23683)