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PARP Inhibitor XII-CAS 489457-67-2-Calbiochem
| 产品编号： | 4083927 |
| 规格： | The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications. |
| CAS NO： | 489457-67-2 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
489457-67-2
PARP Inhibitor XII-CAS 489457-67-2-Calbiochem
3-(4-Chlorophenyl)quinoxaline-5-carboxamide
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H10ClN3O |
| Molecular weight | 283.71 |
| General description【一般描述】 | A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics. |
| Warning【警告】 | Toxicity: Irritant (B) |
| Other Notes【其他说明】 | Ishida, J., et al. 2006. Bioorg. Med. Chem.14, 1378. Iwashita, A., et al. 2005. FEBS Lett.579, 1389. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | light brown |
| solubility【溶解性】 | DMSO: 10 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
