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NS 2028-CAS 204326-43-2-Calbiochem
| 产品编号： | 4083920 |
| 规格： | Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase. |
| CAS NO： | 204326-43-2 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
204326-43-2
NS 2028-CAS 204326-43-2-Calbiochem
4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H5BrN2O3 |
| Molecular weight | 269.05 |
| MDL number | MFCD01530052 |
| General description【一般描述】 | Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase (IC50 = 30 nM for basal and 200 nM for NO-stimulated enzyme activity; IC50 = 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum). |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target basal soluble guanylyl cyclase Target IC50: 30 nM for basal and 200 nM for NO-stimulated enzyme activity; 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C) for long-term storage. DMSO stock solutions are stable for up to 1 month at -20°C and for ~8 h at 4°C. Avoid freeze/thaw cycles of solutions. |
| Other Notes【其他说明】 | Fleming, I., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 1123. Olesen, S.P., et al. 1998. Br. J. Pharmacol. 123, 299. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (NMR) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | chloroform: 1 mg/mL DMSO: 5 mg/mL ethanol: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
