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Tafluprost acid
产品别名
209860-88-8
Tafluprost acid
AFP-172
9α,11α-dihydroxy-15,15-difluoro-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
(5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-Heptenoic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H28F2O5 |
| Molecular weight | 410.45 |
| MDL number | MFCD08062149 |
| Biochem/physiol Actions【生化/生理作用】 | Taflupost acid is the active metabolite of Tafluprost, a prostaglandin F2α agonist that lowers intraocular pressure and is used in the treatment of glaucoma. Taflupost acid has high affinity and selectivity for the prostaglandin PGF2α (FP) receptor with a Ki of 0.4 nM. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | oil |
| optical activity【旋光性】 | [α]/D 17 to 22°, c = 1.0 in methanol |
| color【颜色】 | colorless |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H361d |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Repr. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
