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N-C12-desoxymethylsphinganine
| 产品编号： | 4072606 |
| 规格： | N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder |
| CAS NO： | 1246298-41-8 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246298-41-8
N-C12-desoxymethylsphinganine
N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C29H59NO2 |
| Molecular weight | 453.78 |
| General description【一般描述】 | N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time. |
| Biochem/physiol Actions【生化/生理作用】 | Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860461P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860461P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
