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desmosterol-d6
| 产品编号： | 4071448 |
| 规格： | cholesta-5,24-dien-3β-ol-d6, powder |
| CAS NO： | 1246298-67-8 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246298-67-8
desmosterol-d6
24-dehydrocholesterol(d6); 5,24-cholestadien-3β-ol(d6)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H38OD6 |
| Molecular weight | 390.67 |
| NACRES | NA.25 |
| General description【一般描述】 | Desmosterol constitutes 1% of brain sterol and is catabolized to cholesterol by the enzyme 3-hydroxysterol 24-reductase (DHCR24). It is an intermediate in the Bloch branch of the cholesterol biosynthesis pathway. Desmosterol-d6 is a deuterated form of desmosterol. |
| Application【应用】 | Desmosterol-d6 has been used:
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| Biochem/physiol Actions【生化/生理作用】 | Desmosterol low levels in the hippocampus directly impacts progenitor cell differentiation into neurons. Desmosterol-d6 is used as a substitute to desmosterol in hepatitis C virus (HCV) based viral assays to rescue replication. Desmosterol being a C27 sterol intermediate is implicated in the Alzheimer′s disease (AD) pathogenesis. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700040P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700040P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
