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1-desoxymethylsphinganine
| 产品编号： | 4064235 |
| 规格： | 1-desoxymethylsphinganine (m17:0), powder |
| CAS NO： | 1219484-98-6 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1219484-98-6
1-desoxymethylsphinganine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H37NO |
| Molecular weight | 271.48 |
| General description【一般描述】 | 1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA. |
| Application【应用】 | 1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1. |
| Biochem/physiol Actions【生化/生理作用】 | 1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860473P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC[C@]([H])(O)CCCCCCCCCCCCCCC |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860473P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
