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小鼠PAI-1 ELISA试剂盒
Mouse PAI-1 ELISA Kit
| 产品编号： | 4063926 |
| 规格： | for cell culture supernatants, plasma, and serum samples |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
小鼠PAI-1 ELISA试剂盒
Mouse PAI-1 ELISA Kit
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | This ELISA antibody pair detects mouse and human PAI-1. The PAI-1 (plasminogen activator inhibitor) gene is localized to human chromosome 7q22.1. Active form of PAI-1 is expressed in the blood and tissues. Platelets harbor both the active and latent forms of PAI-1. |
| Application【应用】 | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocolfor details. |
| Biochem/physiol Actions【生化/生理作用】 | PAI-1 (plasminogen activator inhibitor) produced by platelets takes part in stabilizing blood clotting mechanism. PAI-1 prevents plasminogen activation during fibrinolysis. This might lead to the risk of cardiovascular disease. Elevated levels of PAI-1 has been observed in type 2 diabetes mellitus and serves the reason for reduced insulin sensitivity. PAI-1 stimulates the process of cellular senescence. PAI-1 regulation occurs through p53 dependent TGF-β (transforming growth factor-β) signalling. Studies also also predict that stress and depression might influence PAI-1 expression. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
产品性质
| species reactivity | mouse, human |
| technique(s) | ELISA: suitable |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 80 pg/ml |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
