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Granzyme B Inhibitor IV-Calbiochem
| 产品编号： | 4063019 |
| 规格： | The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications. |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Granzyme B Inhibitor IV-Calbiochem
Ac-IEPD-CHO, Caspase-8 inhibitor III
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H34N4O9 |
| Molecular weight | 498.53 |
| General description【一般描述】 | A reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes. A reversible inhibitor of granzyme B and caspase-8. |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Primary Target granzyme B Cell permeable: no Reversible: yes |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Ac-Ile-Glu-Pro-Asp-CHO |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364. Thornberry, N.A., et al. 1997. J. Biol. Chem.272, 17907. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
