L-α-lysophosphatidylinositol Sodium Salt, Soy-CAS 796963-91-2-Calbiochem

C₂₅H₄₈NaO₁₂P

594.61

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Toxicity: Standard Handling (A)

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

>99% (HPLC)

powder

Calbiochem^®

OK to freeze
desiccated (hygroscopic)
protect from light

white

DMSO: soluble

ambient

−20℃

O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

1 mg in Glass bottle
Packaged under inert gas

11 - Combustible Solids

WGK 2