K-252c-CAS 85753-43-1-Calbiochem

C₂₀H₁₃N₃O

311.34

A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC₅₀ = 2.45 µM) and protein kinase A (IC₅₀ = 25.7 µM).
A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (IC₅₀ = 25.7 µM) and protein kinase C (IC₅₀ = 2.45 µM).

Cell permeable: yes
Target IC₅₀: 2.45 µM against protein kinase C
Product competes with ATP.
Reversible: yes
Primary Target
PKC

Toxicity: Standard Handling (A)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Fabre, S., et al. 1993. Bioorg. Med. Chem.1, 193.
Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (HPLC)

solid

Calbiochem^®

OK to freeze

off-white

DMSO: 5 mg/mL
methanol: soluble

ambient

2-8℃

1 mg in Plastic ampoule

GHS07

Warning

H302 - H319

P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313

Acute Tox. 4 Oral - Eye Irrit. 2

11 - Combustible Solids

WGK 3