5-Fluorouracil-CAS 51-21-8-Calbiochem

C₄H₃FN₂O₂

130.08

MFCD00006018

Potent antitumor agent that inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis of human colon cancer cell lines.
Potent antitumor agent. Inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis in human colon cancer cell lines.

Primary Target
Aminoisobutyrate-pyruvate aminotransferase
Product does not compete with ATP.
Reversible: no
Cell permeable: no

Toxicity: Harmful (C)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Pressacco, J., et al. 1996. Br. J. Cancer72, 939.
Shchepotin, I.B., et al. 1994. Anticancer Res.14, 1027.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (HPLC)

solid

Calbiochem^®

OK to freeze

white

hot water: 1 mg/mL
methanol: 1 mg/mL
DMF: 5 mg/mL
DMSO: 5 mg/mL

ambient

2-8℃

1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

GHASVSINZRGABV-UHFFFAOYSA-N

1 g in Glass bottle

GHS06,GHS08

Danger

H301 - H351

P201 - P202 - P264 - P270 - P280 - P301 + P310

Acute Tox. 3 Oral - Carc. 2

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 3