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BID, Caspase-8-cleaved from mouse
| 产品编号： | 3414148 |
| 规格： | ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD03456214 |
| NACRES | NA.32 |
| General description【一般描述】 | Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated. |
| Biochem/physiol Actions【生化/生理作用】 | Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability. |
| Physical form【外形】 | 0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl. |
| Analysis Note【分析说明】 | Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | buffered aqueous solution |
| UniProt accession no.【UniProt登记号】 | P70444 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Bid(12122) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
