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Anti-Rat MKP3 antibody produced in rabbit
| 产品编号： | 3390765 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Rat MKP3 antibody produced in rabbit
Anti-Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis |
| Immunogen【免疫原】 | RAT MKP3 (1-410) This antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1-381 of rat MKP3. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| technique(s) | indirect ELISA: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_446335 |
| UniProt accession no.【UniProt登记号】 | Q64346 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
