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Anti-PARG (N-term) antibody produced in rabbit
| 产品编号： | 3382462 |
| 规格： | saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PARG (N-term) antibody produced in rabbit
Anti-Poly(ADP-ribose) glycohydrolase
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | PARG (Poly ADP-ribose glycohydrolase) is a catabolic enzyme with molecular mass ranging from 60-74kDa. It has four isoforms namely G1, G2, G3 and G4 with high protease sensitivity. |
| Immunogen【免疫原】 | PARG (NP_003622, 329-364) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Parg. |
| Application【应用】 | Anti-PARG (N-term) antibody produced in rabbit is suitable for indirect ELISA (1:1000) and immunohistochemistry (1:50-1:100) applications. |
| Biochem/physiol Actions【生化/生理作用】 | PARG (Poly ADP-ribose glycohydrolase) is involved in several gene regulation processes such as maintenance of chromatin structure, transcription, DNA repair and apoptosis. It regulates retinoic acid receptor (RAR)-mediated transcription during chromatin remodeling. It catabolically separate ADP-ribose polymers synthesized by poly-(ADP-ribose) polymerases. A study shows that PARG plays a therapeutic role in various physiological conditions such as inflammation, ischemia, stroke, and cancer chemotherapy. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_003622 |
| UniProt accession no.【UniProt登记号】 | Q86W56 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PARG(8505) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
