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Anti-JAK2 (Ab-570) antibody produced in rabbit
产品别名
Anti-JAK2 (Ab-570) antibody produced in rabbit
Anti-Janus kinase 2 (a protein tyrosine kinase) antibody produced in rabbit
Anti-JTK10 antibody produced in rabbit
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~125 kDa |
| species reactivity | human, rat |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (G-D-Y-G-Q) |
| NCBI accession no.【NCBI登记号】 | NP_004963.1 |
| UniProt accession no.【UniProt登记号】 | O60674 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... JAK2(3717) |
基本信息
| General description【一般描述】 | JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the the Jak family of protein. It is located on chromosome 9p24. |
| Immunogen【免疫原】 | Peptide sequence around aa. 568-572 (G-D-Y-G-Q), according to the protein JAK2. |
| Biochem/physiol Actions【生化/生理作用】 | JAK2 (janus kinase 2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品说明
| Target description【目标描述】 | Plays a role in leptin signaling and control of body weight. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
