您的位置：首页 > 产品中心 > 1160247-92-6， VU0238429
VU0238429
| 产品编号： | 3259229 |
| 规格： | solubility: ≥20 mg/mL in DMSO |
| CAS NO： | 1160247-92-6 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
1160247-92-6
VU0238429
1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H12F3NO4 |
| Molecular weight | 351.28 |
| MDL number | MFCD16618396 |
| PubChem Substance ID【PubChem化学物质编号】 | 329829052 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | VU0238429 is a selective muscarinic acetylcholine receptor 5 (M5) positive allosteric modulator; causes leftward shift in acetylcholine potency. M5 is thought to regulate cerebral blood flow, and activation of M5 may be therapeutic for Alzheimer′s disease. VU0238429 is the first reported M5-selective small molecule of any kind. It is >30-fold more selective for M5 over M1, M2, M3, and M4. |
| Features and Benefits【特点和优势】 | This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | orange |
| solubility【溶解性】 | DMSO: ≥20 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1ccc(CN2C(=O)C(=O)c3cc(OC(F)(F)F)ccc23)cc1 |
| InChI | 1S/C17H12F3NO4/c1-24-11-4-2-10(3-5-11)9-21-14-7-6-12(25-17(18,19)20)8-13(14)15(22)16(21)23/h2-8H,9H2,1H3 |
| InChI key | CKLGZXFOLMHCMC-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H319 - H400 |
| Precautionary Statements | P273 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
