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Tiludronate disodium salt hydrate
产品别名
89987-06-4
Tiludronate disodium salt hydrate
[[(4-Chlorophenyl)thio]methylene]bisphosphonic acid disodium salt hydrate
Skelid
Tiludronic acid disodium
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C7H7ClNa2O6P2S · xH2O |
| Molecular weight | 362.57 (anhydrous basis) |
| MDL number | MFCD16872037 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826798 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Tiludronate is a bisphosphonate bone resorption inhibitor. Tiludronate inhibits protein-tyrosine-phosphatase, leading to detachment of osteoclasts from the bone surface. It also inhibits the osteoclastic proton pump and is used to treat Paget′s disease. |
| Features and Benefits【特点和优势】 | This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Preparation Note【制备说明】 | Tiludronate disodium salt hydrate is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | H2O: >10 mg/mL, clear |
| originator【创始人】 | Sanofi Aventis |
| SMILES string | O.[Na+].[Na+].OP([O-])(=O)C(Sc1ccc(Cl)cc1)P(O)([O-])=O |
| InChI | 1S/C7H9ClO6P2S.2Na.H2O/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14;;;/h1-4,7H,(H2,9,10,11)(H2,12,13,14);;;1H2/q;2*+1;/p-2 |
| InChI key | SZVJRJRMQCKFON-UHFFFAOYSA-L |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
