您的位置：首页 > 产品中心 > 1164470-53-4， Sal003
Sal003
产品别名
1164470-53-4
Sal003
(2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[[(4-chlorophenyl)amino]thioxomethyl]amino]ethyl]-2-propenamide
3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H15Cl4N3OS |
| Molecular weight | 463.21 |
| MDL number | MFCD00361095 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824543 |
| Application【应用】 | Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells. |
| Biochem/physiol Actions【生化/生理作用】 | Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4. Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated protect from light |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: ≥10 mg/mL |
| compatibility【相容性】 | for use with Bio-Rad CFX96 |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Clc1ccc(NC(=S)NC(NC(=O)\C=C\c2ccccc2)C(Cl)(Cl)Cl)cc1 |
| InChI | 1S/C18H15Cl4N3OS/c19-13-7-9-14(10-8-13)23-17(27)25-16(18(20,21)22)24-15(26)11-6-12-4-2-1-3-5-12/h1-11,16H,(H,24,26)(H2,23,25,27)/b11-6+ |
| InChI key | TVNBASWNLOIQML-IZZDOVSWSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273 - P501 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
