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Saclofen
产品别名
125464-42-8
Saclofen
β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H12ClNO3S |
| Molecular weight | 249.71 |
| MDL number | MFCD00216817 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824485 |
| NACRES | NA.32 |
| Application【应用】 | Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats. Saclofen has been used to prevent the inhibitory action of oxytocin on capsaicin-induced glutamatergic spontaneous excitatory transmission in rat neurons. |
| Biochem/physiol Actions【生化/生理作用】 | Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action. Saclofen is the sulphonic analog of baclofen and is a selective GABAB receptor antagonist. |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | 0.1 M NaOH: 20 mg/mL |
| SMILES string | NCC(CS(O)(=O)=O)c1ccc(Cl)cc1 |
| InChI | 1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14) |
| InChI key | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
| Gene Information | human ... GABBR1(2550), GABBR2(9568) mouse ... GABBR1(54393), GABBR2(242425) rat ... GABBR1(81657), GABBR2(83633) |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
