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Monoclonal Anti-Rhodopsin Kinase 1A antibody produced in mouse
| 产品编号： | 3151466 |
| 规格： | clone G8, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Rhodopsin Kinase 1A antibody produced in mouse
Anti-GRK1a
基本信息
| MDL number | MFCD03457575 |
| NACRES | NA.44 |
| General description【一般描述】 | GRK1 (rhodopsin kinase) is an enzyme that belongs to serine/threonine protein kinase family and expresses mainly in rod and cone photoreceptors. It has a crucial role in phosphorylation of photoactivated rhodopsin and hence starting steps in its deactivation. Monoclonal anti-rhodopsin kinase 1a antibody can be used in immunoprecipitation. Mouse anti-rhodopsin kinase 1a antibody reacts specifically with an epitope present in the C-terminal region of mouse, bovine, rat, chicken and human GRK1a. The product has shown no cross-reactivity with other G protein coupled kinases together with GRK1b. |
| Immunogen【免疫原】 | derived from human GRK1 |
| Application【应用】 | Monoclonal anti-rhodopsin kinase 1a antibody can be used in indirect immunofluorescence and western blotting. |
| Physical form【外形】 | Supplied in phosphate buffered saline containing 0.05% sodium azide. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | G8, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | rat, bovine, human, mouse, chicken |
| technique(s) | immunoprecipitation (IP): suitable indirect immunofluorescence: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q15835 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GRK1(6011) mouse ... Grk1(24013) rat ... Grk1(81760) |
产品说明
| Target description【目标描述】 | Rhodopsin Kinase 1A encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
