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ML169
产品别名
1222878-02-5
ML169
2-[[1-[(5-Bromo-2-fluorophenyl)methyl]-1H-indol-3-yl]sulfonyl]-N-(5-methyl-3-isoxazolyl)-acetamide
VU0405652
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H17BrFN3O4S |
| Molecular weight | 506.34 |
| MDL number | MFCD23704785 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825253 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | ML169 is a positive allosteric modulator (PAM) of the muscurinic acetycholine receptor M1 (CHRM1). ML169 does not cross react with other muscarinic receptors and is able to penetrate the blood brain barrier. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: >5 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cc(Br)ccc3F)c4ccccc24)no1 |
| InChI | 1S/C21H17BrFN3O4S/c1-13-8-20(25-30-13)24-21(27)12-31(28,29)19-11-26(18-5-3-2-4-16(18)19)10-14-9-15(22)6-7-17(14)23/h2-9,11H,10,12H2,1H3,(H,24,25,27) |
| InChI key | RUYRNYRGPSAXTK-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
