1-Pyrenebutyric hydrazide

C₂₀H₁₈N₂O

302.37

MFCD00467260

329769260

NA.32

1-Pyrenebutyric hydrazide (PBH) finds biological/medical applications in the detection, labeling, and quantification of biological carbonyl compounds including aldehydes and/or ketones and carboxylic acids. It is also industrially used in chemo-sensor materials, lubricants, etc.

1-Pyrenebutyric hydrazide may be used as a fluorescence derivatization reagent in the following:

• Determination of succinylacetone (SA) in urine samples of hepatorenal tyrosinemia patients using high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
• Determination of glutaric and 3-hydroxyglutaric acids in urine of glutaric acidemia type I patients using HPLC technique with intramolecular excimer-forming fluorescence derivatization.

Fluorescent labeling reagent for carbonyl compounds, e.g. cyclobutanones formed on food irradiation; Labeling of other compounds

for fluorescence

≥97.0% (T)

167-171 ℃

NNC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34

1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)

SOPPDVMSOKMZOC-UHFFFAOYSA-N

GHS07

Warning

H302 + H312 + H332 - H315 - H319 - H335

P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

13 - Non Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves