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IMB-10
产品别名
307525-40-2
IMB-10
3-(2-methylphenyl)-5-(3-phenyl-2-propen-1-ylidene)-2-thioxo-4-thiazolidinone
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H15NOS2 |
| Molecular weight | 337.46 |
| MDL number | MFCD20134199 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825094 |
| NACRES | NA.77 |
| Application【应用】 | IMB-10 may be used to study integrin-mediated signaling in tumor cells. |
| Biochem/physiol Actions【生化/生理作用】 | IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis. IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: ≥25 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1ccccc1N2C(=S)S\C(=C\C=C\c3ccccc3)C2=O |
| InChI | 1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+ |
| InChI key | UYZLENPCNZVWQZ-QHMSGILQSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
