您的位置：首页 > 产品中心 > 144625-51-4， GR 113808
GR 113808
| 产品编号： | 3092196 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 144625-51-4 |
| 包装规格： | 10 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
144625-51-4
GR 113808
1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H27N3O4S |
| Molecular weight | 393.50 |
| MDL number | MFCD00912901 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278311 |
| NACRES | NA.77 |
| Application【应用】 | GR 113808 has been used as a serotonin receptor 4 (5-HT4R) blocker to study its effects on the calcium (Ca2+) transients in rat ventricular cardiomyocytes. It has also been used as a 5-HT4R antagonist to study its effects on de novo enteric neurogenesis in post-embryonic zebrafish. |
| Biochem/physiol Actions【生化/生理作用】 | GR 113808 is a 5-HT4 serotonin receptor antagonist. |
| Features and Benefits【特点和优势】 | This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from GlaxoSmithKline |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white to light pink |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13 |
| InChI | 1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 |
| InChI key | MOZPSIXKYJUTKI-UHFFFAOYSA-N |
| Gene Information | human ... HTR4(3360) rat ... Htr3a(79246), Htr4(25324) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
